Measuring Fluid Pressure In The Brain Without Surgery

During this time to determine the fluid pressure within the brain (intra cranial pressure) requires an expensivemachine and process operation. But doctors from the Faculty of medicine found a way to measure the fluid in the brain via the blood and cerebrospinal fluidsamples.

Increased intra-cranial pressure is usually caused due to the addition of mass in the cavity of the head as well as congenitalmalformations, especially that disrupt the flow of cerebrospinal fluid.

“Standard standard for measuring intra-cranial pressure by way of a tube into the head of operations connected with the monitor up to Electromagnetic out charts. But these tools are expensive and not a lot,” said Dr. Wismaji Sadewo the sidelines of a promotional event with his doctoral dissertation entitled Oxidative Stress Alert At Increased Intra cranial Pressure on space Pratista FKUI Sena.

Dr. Wismaji said increased intra-cranial pressure monitoring is needed continuously over time, so if there are changes that occur can be specified coping strategies before continuing toward permanent damage.

In a study conducted by Dr. Wismaji found that intra-cranial pressure to learn from a patient can be seen from the four compounds, the enzyme catalase, NADPH reductant, Super oxide Dismutase (SOD) and metabolite MDA.

This is due to the mechanism at the cellular and molecular level could produce a particular compound in the case of increased intra-cranial pressure. The concentration of these four compounds is obtained through the blood and compared with concentrations obtained via the cerebrospinal fluid.

“The blood that can be taken from anywhere, but closer to the brain would be better, whereas for the brain fluid taken from the spinal cord,” said the doctor who was born in Demak 42 years ago.

Blood and cerebrospinal fluid is taken will be sent to the laboratory and inserted in a program that can be known how much pressure the intra kranialnya, whether including normal (<10 cm H2O), rose a mild (10-15 cm H2O), up is (16 – 25 cm H2O) and high pressure (> 25 cm H2O).

The study, conducted over four years involving 24 respondents who had 3-63 year age range. The cause of thedisease also varies the stroke hemorajik many as 9 cases, 5 cases of trauma, neoplasm 7 cases and other cases as much as 3.

The study results if the value of SOD get down, down, and MDA increased NADPH show a person has a disorder with intra kranialnya. Whereas a low amount of enzyme catalase showed an increase in intra-cranial pressure is high.

“The value of intra-cranial pressure is known to be used for diagnosis, determining prognosis of disorders that exist, to determine further therapeutic strategies and evaluating treatment outcomes have been done,” he said.

Dr. Wismaji hope with the discovery of this, intra-cranial pressure measurements can be made easier so that the treatment given to patients to be more precise.